ISOLATION AND STRUCTURAL ELUCIDATION OF AN ALKALOID FROM THE RESIN OF Maquira coriacea (Karsten) Cc.Berg

  • Luis Monsalve Ocmin
  • O. Nino Castro Mandujano
DOI: https://doi.org/10.37761/rsqp.v88i3.399
Keywords: Resin, Maquira Coriacea, alkaloids, bis-benzylisoquinoline

Abstract

The resin of the Maquira coriacea is popular in traditional medicine in the communities of Peru, currently lacking phytochemical studies; therefore, the objective of the investigation is to isolate and elucidate the alkaloids present. The resin was subjected to hydroalcoholic extraction by maceration, and 2 alkaloids were extracted, one was isolated and identified with a retention factor (Rf2) 0.97. The wavelengths (λ) reported in ultraviolet visible spectroscopy (UV-VIS) were λ=226 nm maximum and λ=260 nm minimum; 1H, 13C and
two-dimensional nuclear magnetic resonance (NMR) chemical shifts (δ) report characteristic shifts for bis-benzylisoquinoline alkaloids, and Hybrid Quadrupole Time High Resolution Mass Spectrometry (HRMS-Q) gave a mass of m/s =758.31, allowing the identification of a taligrisin-type base bis-benzylisoquinoline alkaloid (M. Coriacina). Finally, the total alkaloid content of 175 mg of Atropine (AT)/100g of Maquira coriácea resin is reported.

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Author Biographies

Luis Monsalve Ocmin

Facultad de Química e Ing. Química, Universidad Nacional Mayor de san Marcos, Calle Amezaga 375, Cercado
de Lima, Lima, Perú

O. Nino Castro Mandujano

Facultad de Química e Ing. Química, Universidad Nacional Mayor de san Marcos, Calle Amezaga 375, Cercado
de Lima, Lima, Perú

Published
2022-09-30
Issue
Vol. 88 No. 3 (2022): Revista de la Sociedad Química del Perú
Section
Artículos
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This work is licensed under a Creative Commons Attribution 4.0 International License.

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